Through the years, the evolution of medical science and the benefits that came with it has been evident. It continues to search for solutions and effective treatments to many different diseases. Among the most notable and remarkable breakthroughs of the industry is its discovery on liposome. This is now used to ensure success in organ transplant surgeries, treat many medical anomalies and enhance the efficiency of drugs being administered.
The liposomes are tiny, microscopic vesicles which are produced and developed in laboratories. These are made of phospholipids, which are extracted from other sources or produced by natural means. The outer wall of the vesicles has similar composition as a cell wall. Hence, it can interact with the cells directly. These tiny, sphere-shaped bubbles typically have watery core.
The most common use of this structure is to introduce medicines to the patient's body more effectively. The unique property of the vesicles allow drugs to be delivered in specific parts of the body through diffusion. With its double-layered membranes, the vesicle can carry hydrophobic drugs. This can also be used to carry biological agents like antibodies to targeted parts in the patient's body.
Moreover, this can extend the delivery time of the administered drugs. The bi-layered sphere slowly releases the drugs in interval over a period of time. This is hypothetically believed to help reduce side-effects since the direct impact of the applied medications are limited only to the affected tissues. This also means that the efficiency of the drugs is maximized.
The vesicles are also believed to be an effective cancer fighting agent. The spheroids can mark the cancer cells. It can also slip right to the tumor by going through the blood flow. This stays in the bloodstreams as well because of its miniature size and its property that is similar to the blood vessels. The drug vessels cannot pass through the endothelial wall as opposed to cancer cells, which are naturally leaky.
Autoimmune diseases may also be combated by using the spheroids. In a transplant surgery, the body usually identifies the newly harvested organ to be a foreign entity. The body's natural protection, the immune system, may attack the organ in an attempt to prevent possible infestation. This could lead to transplant rejection. The artificial lipid is used to suppress the function of the immune system and slow down its progress.
The drug vesicles are not spontaneously produced, though. There are several artificial methods used in producing the spheroids depending on its use and function. The production methods and structure must be determined beforehand. One aspect to consider is the method of dissemination as well as the type of material that it carries.
These vesicles come in various sizes. The vessels are typically small for the white blood cells to easily engulf the bubbles before the drug it carries can be released. Prior to its production, the size and numbers of vesicles to be created have to be determined. Possibilities of reproduction must also be anticipated.
The only possible disadvantage with liposome is the cost of producing it. Mass production is not currently feasible because the vessels do not last long following its creation. Stability may also be an issue. On occasion, the drugs may be mixed unintentionally. Other than that, this is a promising breakthrough.
The liposomes are tiny, microscopic vesicles which are produced and developed in laboratories. These are made of phospholipids, which are extracted from other sources or produced by natural means. The outer wall of the vesicles has similar composition as a cell wall. Hence, it can interact with the cells directly. These tiny, sphere-shaped bubbles typically have watery core.
The most common use of this structure is to introduce medicines to the patient's body more effectively. The unique property of the vesicles allow drugs to be delivered in specific parts of the body through diffusion. With its double-layered membranes, the vesicle can carry hydrophobic drugs. This can also be used to carry biological agents like antibodies to targeted parts in the patient's body.
Moreover, this can extend the delivery time of the administered drugs. The bi-layered sphere slowly releases the drugs in interval over a period of time. This is hypothetically believed to help reduce side-effects since the direct impact of the applied medications are limited only to the affected tissues. This also means that the efficiency of the drugs is maximized.
The vesicles are also believed to be an effective cancer fighting agent. The spheroids can mark the cancer cells. It can also slip right to the tumor by going through the blood flow. This stays in the bloodstreams as well because of its miniature size and its property that is similar to the blood vessels. The drug vessels cannot pass through the endothelial wall as opposed to cancer cells, which are naturally leaky.
Autoimmune diseases may also be combated by using the spheroids. In a transplant surgery, the body usually identifies the newly harvested organ to be a foreign entity. The body's natural protection, the immune system, may attack the organ in an attempt to prevent possible infestation. This could lead to transplant rejection. The artificial lipid is used to suppress the function of the immune system and slow down its progress.
The drug vesicles are not spontaneously produced, though. There are several artificial methods used in producing the spheroids depending on its use and function. The production methods and structure must be determined beforehand. One aspect to consider is the method of dissemination as well as the type of material that it carries.
These vesicles come in various sizes. The vessels are typically small for the white blood cells to easily engulf the bubbles before the drug it carries can be released. Prior to its production, the size and numbers of vesicles to be created have to be determined. Possibilities of reproduction must also be anticipated.
The only possible disadvantage with liposome is the cost of producing it. Mass production is not currently feasible because the vessels do not last long following its creation. Stability may also be an issue. On occasion, the drugs may be mixed unintentionally. Other than that, this is a promising breakthrough.
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